IgE responses to bluetongue virus (BTV) serotype 11 after immunization with inactivated BTV and challenge infection.

@article{Oden1999IgERT,
  title={IgE responses to bluetongue virus (BTV) serotype 11 after immunization with inactivated BTV and challenge infection.},
  author={Anselmo Carlos Ode{\'o}n and Laurel J. Gershwin and Bennie Irve Osburn},
  journal={Comparative immunology, microbiology and infectious diseases},
  year={1999},
  volume={22 2},
  pages={145-62}
}
To test the hypothesis that development of a BTV-specific IgE response plays a role in clinical disease manifestation, the humoral immune response of cattle to inactivated and virulent BTV was studied. Three calves received three sensitizing immunizations of inactivated BTV, 3 weeks apart. The BTV-sensitized animals, two non-sensitized BTV-seropositive and 4 BTV-seronegative control cattle. were challenge-exposed with BTV-11, UC8 strain. All cattle inoculated with inactivated BTV developed… CONTINUE READING