IgE-receptor activated chloride uptake in relation to histamine secretion from rat mast cells.

@article{Friis1994IgEreceptorAC,
  title={IgE-receptor activated chloride uptake in relation to histamine secretion from rat mast cells.},
  author={Ulla G. Friis and T. Stroem Johansen and Neil Allen. Hayes and John C. Foreman},
  journal={British journal of pharmacology},
  year={1994},
  volume={111 4},
  pages={
          1179-83
        }
}
1. Antigen-stimulated histamine secretion from rat peritoneal mast cells was inhibited when extracellular chloride was replaced by either isethionate or gluconate anions, but the histamine release still remained quite substantial. 2. Rat peritoneal mast cells take up 36Cl and the uptake reaches a steady state after 60 min incubation with the isotope. At steady state, the intracellular chloride level in the cells was calculated to be 29 +/- 11.5 mM. 3. The chloride uptake in mast cells was… CONTINUE READING
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