IgE reactivity against a cross-reactive allergen in crustacea and mollusca: evidence for tropomyosin as the common allergen.

@article{Leung1996IgERA,
  title={IgE reactivity against a cross-reactive allergen in crustacea and mollusca: evidence for tropomyosin as the common allergen.},
  author={Patrick S. C. Leung and Wan Ki Chow and Susan Duffey and Hoi Shan Kwan and M Eric Gershwin and K H Chu},
  journal={The Journal of allergy and clinical immunology},
  year={1996},
  volume={98 5 Pt 1},
  pages={954-61}
}
BACKGROUND Although cross-reactivity between mollusks and other crustaceans in shrimp-sensitive subjects has been reported, the mechanism of this allergenic cross-reactivity has not been studied in detail. OBJECTIVE To investigate this cross-reactivity in vitro, we have taken advantage of a complementary DNA that expresses tropomyosin, the immunodominant shrimp allergen. METHODS Serum IgE from nine patients with known anaphylaxis to shrimp and five normal volunteers were analyzed by… CONTINUE READING
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