IgE-mediated asthma and rhinitis I: a role of allergen exposure?

@article{Nielsen2002IgEmediatedAA,
  title={IgE-mediated asthma and rhinitis I: a role of allergen exposure?},
  author={Gunnar Damg{\aa}rd Nielsen and Jitka Stilund Hansen and Rikke M Lund and Mette Bergqvist and S{\o}ren Thor Larsen and Susanne Knoth Clausen and Peter Thygesen and Otto Melchior Poulsen},
  journal={Pharmacology & toxicology},
  year={2002},
  volume={90 5},
  pages={
          231-42
        }
}
Exposures to airborne protein antigens, aeroallergens, may cause sensitization with production of Th2-dependent antibodies, including IgE. The IgE antibodies and associated cellular responses are responsible for the allergic airway diseases, allergic rhinitis and allergic asthma, which are increasing in societies with Western life style. Aeroallergens may have different potential to sensitize exposed subjects. Thus, there are only a limited number of important groups of aeroallergens, which are… CONTINUE READING
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