IgE expression pattern in lung: relation to systemic IgE and asthma phenotypes.

@article{Balzar2007IgEEP,
  title={IgE expression pattern in lung: relation to systemic IgE and asthma phenotypes.},
  author={Silvana Balzar and Matthew Strand and Diane K Rhodes and Sally E Wenzel},
  journal={The Journal of allergy and clinical immunology},
  year={2007},
  volume={119 4},
  pages={855-62}
}
BACKGROUND IgE-mediated responses contribute to allergy and asthma. Little is understood regarding the relationship of tissue IgE to systemic IgE, inflammation or clinical outcomes. OBJECTIVES To evaluate local IgE expression and cellular inflammation in the proximal and distal lung of normal subjects and subjects with asthma of varying severity and relate those tissue parameters to systemic IgE levels, atopy, lung function, and history of severe exacerbations of asthma. METHODS Tissue from… CONTINUE READING
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