IgE antibody quantification and the probability of wheeze in preschool children.

@article{Simpson2005IgEAQ,
  title={IgE antibody quantification and the probability of wheeze in preschool children.},
  author={Angela Simpson and Lars Soderstrom and Staffan Ahlstedt and Clare S. Murray and Ashley Woodcock and Adnan Custovic},
  journal={The Journal of allergy and clinical immunology},
  year={2005},
  volume={116 4},
  pages={744-9}
}
BACKGROUND IgE-mediated sensitization is usually considered a dichotomous variable (either sensitized or not). Quantitative IgE antibody analysis may better predict the expression of wheeze. OBJECTIVE Within the context of a population-based birth cohort, we investigated the association among wheeze, lung function, and specific IgE antibody levels. METHODS Children (n = 521) were followed to age 5 years with repeated questionnaires, skin testing, and measurement of lung function (specific… CONTINUE READING