IgE antibodies to Plasmodium falciparum and severity of malaria in children of one ethnic group living in Burkina Faso.

@article{Calissano2003IgEAT,
  title={IgE antibodies to Plasmodium falciparum and severity of malaria in children of one ethnic group living in Burkina Faso.},
  author={Carlo Calissano and David Laurence Modiano and Bienvenu Sodiomon Sirima and Amadou M Konat{\'e} and Issa Sanou and Alphonse Sawadogo and Hedvig Perlmann and Marita Troye-Blomberg and Peter Perlmann},
  journal={The American journal of tropical medicine and hygiene},
  year={2003},
  volume={69 1},
  pages={31-5}
}
Plasmodium falciparum malaria infection induces elevated blood levels of both total immunoglobulin and anti-plasmodial antibodies belonging to different isotypes. We have previously shown that donors living in areas of malaria transmission develop malaria-specific IgE antibodies that are present at highest concentrations in patients with severe disease, suggesting a role for this isotype in malaria pathogenesis. To establish the possible importance of IgE in the course and severity of this… CONTINUE READING

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