IgD/λ plasmocytoma with immunoglobulin κ light-chain genes in the germ-line configuration

@article{Hauke2004IgDPW,
  title={IgD/λ plasmocytoma with immunoglobulin κ light-chain genes in the germ-line configuration},
  author={Gerhard Hauke and J{\"o}rg T. Epplen and Johanna Chluba and Anna Hollmann and Hans Hartmut Peter},
  journal={Journal of Clinical Immunology},
  year={2004},
  volume={8},
  pages={407-413}
}
Human immunoglobulin (Ig) genes are rearranged in an ordered sequence of events during B-cell differentiation: starting at the IgH locus, a productive VHDJH rearrangement leads to the expression of μ chains. Light-chain gene rearrangements have been found in pre-B cells which express μ chains. In these cells rearrangements of Ig κ light-chain genes precede… CONTINUE READING