IgA antibodies to a protective antigen in human Schistosomiasis mansoni.

@article{Grzych1993IgAAT,
  title={IgA antibodies to a protective antigen in human Schistosomiasis mansoni.},
  author={J. M. Grzych and D Grezel and Chuanyou Xu and J. L. Neyrinck and Monique Capron and John Henry Ouma and Anthony E. Butterworth and Andr{\'e} Capron},
  journal={Journal of immunology},
  year={1993},
  volume={150 2},
  pages={527-35}
}
The specific IgA antibody responses to the protective recombinant Schistosoma mansoni 28-kDa glutathione-S-transferase (Sm28GST) Ag and to derived synthetic peptides have been evaluated before and 6 mo after chemotherapy in S. mansoni-infected patients from Kenya. These studies revealed a parallelism between the age-dependent evolution of IgA antibody levels to Sm28GST and to one synthetic peptide (115-131) and the acquisition of resistance to reinfection. Functional analysis revealed that IgA… CONTINUE READING

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