IgA IMMUNE COMPLEXES IN HENOCH-SCHÖNLEIN PURPURA

@article{Levinsky1979IgAIC,
  title={IgA IMMUNE COMPLEXES IN HENOCH-SCH{\"O}NLEIN PURPURA},
  author={RolandJ. Levinsky and Thomas M. Barratt},
  journal={The Lancet},
  year={1979},
  volume={314},
  pages={1100-1103}
}
Raised levels of IgA immune complexes were found in 13 of 18 children with Henoch-Schönlein purpura irrespective of whether they developed nephritis or not. In contrast, only those children who developed nephritis had raised levels of IgG immune complexes as well. In 2 children with nephritis, two discrete peaks of IgA complexes were found, corresponding to 4 x 10(5) to 8 x 10(5) and 2.5 x 10(6) to 4 x 10(6) daltons. IgG complexes were found only in the larger-molecular-weight peak. Such… CONTINUE READING

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