Idiotype as a tumor-specific marker in childhood B cell acute lymphoblastic leukemia.


Immunoglobulin (Ig) or idiotype (Id) is a tumor-specific target in those B cell malignancies that express this molecule on their surface. We explored the biology of B cell acute lymphoblastic leukemia (B cell ALL) using Id as a tumor marker. In this report we describe the development of anti-Id monoclonal antibodies (MAB) for two children with B cell ALL… (More)


4 Figures and Tables

Slides referencing similar topics