Idiopathisches multiples Pigmentsarkom der Haut

  title={Idiopathisches multiples Pigmentsarkom der Haut},
  journal={Archiv f{\"u}r Dermatologie und Syphilis},
  • Kaposi
  • Published 1 June 1872
  • Medicine
  • Archiv für Dermatologie und Syphilis
Humanized Mice as a Model to Study Human Viral Pathogenesis and Novel Antiviral Drugs
It is shown that these mice sustain long term engraftment and systemic expansion of human cells, including the major targets of Kaposi’s sarcoma Herpesvirus (KSHV) and Human immunodeficiency virus type 1 (HIV-1), in peripheral blood and different lymphoid organs.
Utilising omics approaches to understand Kaposi's sarcoma-associated herpesvirus
Light is shed on previously unidentified mechanisms employed by KSHV to hijack the host cell, and may aid in the development of novel therapeutics against this important pathogen.
Characterisation of the interactions between the KSHV ORF57 protein and the human TREX complex
A series of compounds are presented that are able to prevent both KSHV and HSV-1 lytic replication, and a hit compound identified was shown to disrupt formation of the vRNP, lytic protein expression and infectious virions, while allowing endogenous hTREX formation within a therapeutic window, where no cytotoxicity was observed.
Identification of novel tumor predisposition families and underlying genetic defects
A registry based familial clustering of cancers in Finland based on STAT4 as a candidate susceptibility gene for Kaposi sarcoma and the results show that STAT4 activation is not affected by p.Thr446Ile mutation.
KSHV: pathways to tumorigenesis and persistent infection.
Whole-exome sequencing-based discovery of STIM1 deficiency in a child with fatal classic Kaposi sarcoma
Whole-exome sequencing reveals a homozygous splice-site mutation in the gene encoding STIM1 in a child with classic Kaposi sarcoma.
Case Report: Successful Treatment of Kaposi’s Sarcoma With Anlotinib in an HIV-Negative Patient After the Treatment of Drug Reaction With Eosinophilia and Systemic Symptoms Accessory Tragus
This case indicates that anlotinib may be a potential treatment option for Kaposi’s Sarcoma, a neoplasm derived from endothelial cells and associated with human herpesvirus-8 (HHV-8) infection, in an 84-year-old man with a history of psoriasis.
Molecular Mechanisms of Kaposi Sarcoma Development
Kaposi’s sarcoma-associated herpes virus (KSHV) is the underlying cause of this disease and impairs the immune response by various mechanisms such as the degradation of a variety of proteins involved in immune response or binding to cellular chemokines.
Vascular Tumors