Idiopathic retroperitoneal fibrosis: a review of the pathogenesis and approaches to treatment.

  title={Idiopathic retroperitoneal fibrosis: a review of the pathogenesis and approaches to treatment.},
  author={Richard D. Swartz},
  journal={American journal of kidney diseases : the official journal of the National Kidney Foundation},
  volume={54 3},
Idiopathic retroperitoneal fibrosis (IRPF) is an increasingly recognized syndrome. The development of inflammation and fibrosis in the retroperitoneum most often results in a periaortic mass on computed tomography or magnetic resonance imaging that causes pain and constitutional symptoms. Its organ involvement results in urinary tract obstruction, bowel dysfunction, and venous compression with leg swelling, or thrombosis. The syndrome appears autoimmune in nature, but has no specific… CONTINUE READING


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