Idiopathic pulmonary fibrosis: current concepts.

  title={Idiopathic pulmonary fibrosis: current concepts.},
  author={Jay H Ryu and Thomas Vail Colby and Thomas E. Hartman},
  journal={Mayo Clinic proceedings},
  volume={73 11},
Idiopathic pulmonary fibrosis (IPF) is generally defined as a progressive, fibrosing inflammatory disease of the lung parenchyma of unknown cause. It is characterized by slowly increasing dyspnea, diffuse interstitial lung infiltrates, restrictive lung dysfunction, and impaired gas exchange. Ultimately, it is fatal in most patients, and treatment options remain unsatisfactory. The advent of high-resolution computed tomography of the chest and modifications in the histopathologic classification… CONTINUE READING


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