Idiopathic pulmonary fibrosis: an altered fibroblast proliferation linked to cancer biology.

@article{Vancheri2012IdiopathicPF,
  title={Idiopathic pulmonary fibrosis: an altered fibroblast proliferation linked to cancer biology.},
  author={Carlo Vancheri},
  journal={Proceedings of the American Thoracic Society},
  year={2012},
  volume={9 3},
  pages={
          153-7
        }
}
The fibrotic process that characterizes idiopathic pulmonary fibrosis (IPF) is commonly considered the result of a recurrent injury to the alveolar epithelium followed by an uncontrolled proliferation of fibroblasts. However, based on considerable scientific evidence, it has been recently hypothesized that IPF might be considered a neoproliferative disorder of the lung because this disease exhibits several pathogenic features similar to cancer. Indeed, epigenetic and genetic abnormalities… CONTINUE READING
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