Idiopathic intracranial hypertension

@article{Wakerley2015IdiopathicIH,
  title={Idiopathic intracranial hypertension},
  author={B R Wakerley and M. M. X. Tan and EY Ting},
  journal={Cephalalgia},
  year={2015},
  volume={35},
  pages={248 - 261}
}
Background Idiopathic intracranial hypertension or pseudotumour cerebri is primarily a disorder of young obese women characterised by symptoms and signs associated with raised intracranial pressure in the absence of a space-occupying lesion or other identifiable cause. Summary The overall incidence of idiopathic intracranial hypertension is approximately two per 100,000, but is considerably higher among obese individuals and, given the global obesity epidemic, is likely to rise further. The… 

Figures and Tables from this paper

Idiopathic Intracranial Hypertension (Pseudotumor Cerebri)
  • S. Bell
  • Medicine
    The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses
  • 2016
TLDR
An overview for the neuroscience nurse of the clinical features, diagnostic work-up, and therapeutic options available for patients with idiopathic intracranial hypertension is provided.
Idiopathic intracranial hypertension
TLDR
It is shown that the incidence of IIH in obese women is increasing, and epidemiological data demonstrate the increase in incidence in this group: 323 cases per 100,000.
Current concepts in pseudotumor cerebri.
TLDR
Recent changes in defining IIH, understanding the impact and treatment of mild visual loss, and the roles that cerebral venous stenting and optical coherence tomography might have in clinical practice provide the framework to better treat patients with IIH.
Management of Idiopathic Intracranial Hypertension: Experience of a North African Center
TLDR
The IIH is predominantly a disease of women in the childbearing age; surgical treatment is a good option for patients who resisted medication or did not tolerate it as well as for ICH fulminous in emergency cases.
Idiopathic intracranial hypertension without papilledema in children: A case series
TLDR
This case series demonstrates that idiopathic intracranial hypertension can manifest in the absence of clinically obvious papilledema, and has, as such, the potential to cause permanent visual loss if the diagnosis is missed.
Update on Idiopathic Intracranial Hypertension
TLDR
A number of uncontrolled interventional studies have shown transverse sinus stenting to be a potentially effective treatment for medically refractory IIH and medical therapy with acetazolamide should be considered in addition to structured weight loss in patients with mild IIH.
A clinical and radiological study in patients with idiopathic intracranial hypertension
TLDR
Headache is the most common presentation of IIH, and its severity is positively correlation with papilledema grade, and CSF pressure is also positively correlated with papillema grade.
Dural sinus collapsibility, idiopathic intracranial hypertension, and the pathogenesis of chronic migraine
TLDR
The control of intracranial pressure is to be considered a promising new therapeutic target in CM.
Role of imaging in pseudotumor cerebri syndrome
Idiopathic intracranial hypertension presenting with isolated unilateral facial nerve palsy: a case report
TLDR
Idiopathic intracranial hypertension should be suspected in obese young women presenting with headache and transient visual complaints and some cranial nerve abnormalities, which needs a high index of suspicion by clinicians.
...
...

References

SHOWING 1-10 OF 131 REFERENCES
IDIOPATHIC INTRACRANIAL HYPERTENSION (PSEUDOTUMOR CEREBRI): A REAPPRAISAL
TLDR
All neurologists should be familiar with the symptoms and signs as well as the evaluation and treatment of idiopathic intracranial hypertension, a condition seen in obese women of childbearing age.
Update on the pathophysiology and management of idiopathic intracranial hypertension
TLDR
Treatment studies show that the diagnostic lumbar puncture is a valuable intervention beyond its diagnostic importance, and that weight management is critical, but many questions remain regarding the efficacy of acetazolamide, CSF shunting procedures and cerebral transverse venous sinus stenting.
Drugs used in childhood idiopathic or benign intracranial hypertension
  • Y. Matthews
  • Medicine
    Archives of Disease in Childhood - Education and Practice
  • 2008
TLDR
This article provides a comprehensive review of clinical knowledge in childhood IIH and its various treatment modalities with an emphasis on the drugs used and highlights that current management is not evidence based and that well-designed multicentre randomised controlled trials are urgently needed.
Pediatric idiopathic intracranial hypertension.
Advancement in idiopathic intracranial hypertension pathogenesis: focus on sinus venous stenosis
TLDR
The proposed mechanisms predict the long-term remission of IIH syndromes frequently observed after a single or few serial CSF subtractions by lumbar puncture, and lead to a self-sustained intracranial hypertension in presence of a wide range of triggering factors.
Intracranial Hypertension in Systemic Lupus Erythematosus
TLDR
Steroid withdrawal in the treatment of the SLE may be a predisposing or precipitating factor in the development of IH in these patients rather than the inflammatory effects of SLE per se, and the hypercoagulable state in some patients with Sle may also produce cerebral venous sinus thrombosis as an additional potential mechanism of Ih.
Venous sinus stenting for idiopathic intracranial hypertension: a review of the literature
TLDR
In patients with focal venous sinus stenosis, endovascular stent placement across the stenotic sinus region represents an effective treatment strategy with a high technical success rate and decreased rate of complications compared with treatment modalities currently used.
Symptoms and disease associations in idiopathic intracranial hypertension (pseudotumor cerebri)
TLDR
It is concluded that previous studies of IIH, mostly uncontrolled and retrospective, have underestimated the frequency of symptoms in IIH patients and reported chance and spurious associations with common medical conditions and medications.
Primary Spontaneous Cerebrospinal Fluid Leaks and Idiopathic Intracranial Hypertension
TLDR
CSF leak occasionally may keep IIH patients symptom-free; however, classic symptoms and signs of intracranial hypertension may develop after a CSF leak is repaired, exposing these patients to a high risk of recurrence of the leak unless an ICP-lowering intervention is performed.
Idiopathic intracranial hypertension: Can studies of obesity provide the key to understanding pathogenesis?
TLDR
Investigations that evaluate obesity, fat metabolism, endocrinological dysregulation and thrombotic tendency in patients with IIH are required so that pathogenic mechanisms can be clarified and management strategies in IIH can be improved.
...
...