Idiopathic impaired spermatogenesis: genetic epidemiology is unlikely to provide a short-cut to better understanding.


The aetiology of impaired spermatogenesis is unknown in the majority of subfertile men. From several studies of concordance for involuntary childlessness among men, we can conclude that there is a substantial familial component in male subfertility and that shared loci segregating through families can be assumed. We now know that deletions on the Y… (More)