Idiopathic hypersomnia.

  title={Idiopathic hypersomnia.},
  author={Michel M. Billiard},
  journal={Neurologic clinics},
  volume={14 3},
  • M. Billiard
  • Published 1996
  • Medicine, Psychology
  • Neurologic clinics
Idiopathic hypersomnia is not as well delineated as narcolepsy and its history is much more recent. There are at least two forms of the disorder: (1) a polysymptomatic form, characterized by excessive daytime sleepiness, nocturnal sleep of abnormally long duration, and signs of sleep drunkenness on awakening, and (2) a monosymptomatic form that manifests only by excessive daytime sleepiness. The most widely used laboratory procedures are nocturnal polysomnographic recording following by an MSLT… 
Idiopathic Hypersomnia.
There are a number of cases of isolated excessive daytime sleepiness with no prolonged night sleep, no difficulty waking up, which lay between narcolepsy and genuine idiopathic hypersomnia and there is a definite need to further develop laboratory investigations to help identify and classify these cases.
Idiopathic Hypersomnia: Historical Account, Critical Review of Current Tests and Criteria, Diagnostic Evaluation in the Absence of Biological Markers and Robust Electrophysiological Diagnostic Criteria
This review is a critical review of both current ICSD-3 diagnostic criteria and clinical features, scales and questionnaires, electrophysiological and circadian control tests, research techniques, currently used to diagnose idiopathic hypersomnia.
NSS_A_266090 311..322
A critical review of both current ICSD-3 diagnostic criteria and clinical features, scales and questionnaires, electrophysiological and circadian control tests, research techniques, currently used to diagnose idiopathic hypersomnia, and a diagnostic evaluation of this sleep disorder, in the absence of biologic markers and of robust electrophYSiological diagnostic criteria.
Idiopathic hypersomnia with and without long sleep time: a controlled series of 75 patients.
Hypersomnia, especially with long sleep time, is frequently associated with evening chronotype and young age, and is inadequately diagnosed using MSLT.
Update on the Treatment of Idiopathic Hypersomnia
It is reasonable to start with modafinil as a first choice treatment for idiopathic hypersomnia, and methylphenidate and dexamphetamine are good alternatives.
Subjective symptoms in idiopathic hypersomnia: beyond excessive sleepiness
Mental fatigability, dependence on other people for awakening them, and a reduced benefit from usually alerting conditions (except being hyperactive or stressed) seem to be more specific of the daily problems of patients with idiopathic hypersomnia than daytime sleepiness.
Electroencephalographic Markers of Idiopathic Hypersomnia: Where We are and Where We are Going
Current and potential markers of idiopathic hypersomnia are presented, with a focus on sleep propensity, and EEG changes occurring in sleep deprivation conditions and recovery nights, as well as those observed in other central hypersomnolence conditions, namely narcolepsy type-1 and type-2.
A comparison of idiopathic hypersomnia and narcolepsy-cataplexy using self report measures and sleep diary data.
  • D. Bruck, J. Parkes
  • Psychology, Medicine
    Journal of neurology, neurosurgery, and psychiatry
  • 1996
The IH group reported more consolidated nocturnal sleep, a lower propensity to nap, greater refreshment after naps, and a greater improvement in excessive daytime sleepiness since onset than the NLS group.
Narcolepsy and Other Central Disorders of Hypersomnolence
Hypnagogic hallucinations are realistic dream‐like experiences around sleep onset whereas the term 'hypnopompic' is used if they occur from awakening, and Pharmacotherapy for sleepiness should be tailored towards the individual patient.
Polysomnographic study of nocturnal sleep in idiopathic hypersomnia without long sleep time
A peculiar profile of microstructural sleep abnormalities may contribute to sleep fragmentation and, possibly, EDS in IH.


A 19‐h spontaneous sleep period in idiopathic central nervous system hypersomnia
Polysomnographic recordings showed a spontaneous sleep period of 19.4 h and a normal Multiple Sleep Latency Test, which is clearly abnormal but essentially different from those of narcolepsy.
Cataplexy and monoamine oxidase deficiency in Norrie disease
The coexistence of cataplexy and abnormal REM sleep organization with Norrie disease is reported and it is suggested that abnormal MA0 activity or an imbalance between serotonin and other neurotransmitter levels may be involved in the pathogenesis of human catapLexy.
Delayed sleep phase syndrome. A chronobiological disorder with sleep-onset insomnia.
A new syndrome called "delayed sleep phase insomnia" is described, which is proposed to be a disorder of the circadian sleep-wake rhythm in which the "advance" portion of the phase response curve is small.