Idiopathic gigantomastia: newer mechanistic insights implicating the paracrine milieu

  title={Idiopathic gigantomastia: newer mechanistic insights implicating the paracrine milieu},
  author={Liza Das and A. Rai and K. Vaiphei and Akhil Garg and Subair Mohsina and A. Bhansali and P. Dutta and S. Tripathy},
  pages={166 - 177}
  • Liza Das, A. Rai, +5 authors S. Tripathy
  • Published 2019
  • Medicine
  • Endocrine
  • Gigantomastia refers to pathological breast enlargement usually occurring in the peripubertal or peripartum period. Idiopathic gigantomastia, however, is a rare entity with hypotheses citing local expression of hormones and growth factors in causing this disease, none of which have been systemically analysed. The purpose of this study was to delve deeper into the mechanistic pathways causing this condition. Herein, we describe three patients of idiopathic gigantomastia, all of whom had had… CONTINUE READING
    1 Citations
    Body size measurements, digit ratio (2D:4D) and oestrogen and progesterone receptors’ expressions in juvenile gigantomastia


    Breast inflammatory gigantomastia in a context of immune-mediated diseases.
    • 39
    • PDF
    Gestational Gigantomastia Complicated by PTHrP-Mediated Hypercalcemia
    • 8
    • PDF
    Gigantomastia--a classification and review of the literature.
    • 109
    • Highly Influential
    Loss of imprinting of IGF2 in fibroadenomas and phyllodes tumors of the breast.
    • 1
    • PDF
    Macroprolactinemia: Diagnostic, Clinical, and Pathogenic Significance
    • 58
    • PDF
    An idiopathic gigantomastia
    • 12
    • PDF
    Pseudoangiomatous Stromal Hyperplasia: A Rare Cause of Idiopathic Gigantomastia
    • 6
    D penicillamine and breast enlargement.
    • 13
    • PDF