Idiopathic Short QT Interval:A New Clinical Syndrome?

  title={Idiopathic Short QT Interval:A New Clinical Syndrome?},
  author={I. Gussak and P. Brugada and J. Brugada and R. Wright and S. Kopecky and B. Chaitman and P. Bjerregaard},
  pages={99 - 102}
In this first clinical report of an idiopathic familial persistently short QT interval (QTI), we describe three members of one family (a 17-year-old female, her 21-year-old brother, and their 51-year-old mother) demonstrating this ECG phenomenon, associated in the 17-year-old with several episodes of paroxysmal atrial fibrillation requiring electrical cardioversion. Similar ECG changes seen in an unrelated 37-year-old patient were associated with sudden cardiac death. Our report also describes… Expand
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A teenage boy who suffered a witnessed ventricular fibrillation arrest and was subsequently diagnosed with short QT syndrome is reported and additional data from nine other pediatric patients diagnosed with SQTS are presented. Expand
Long QT Syndrome
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The short QT syndrome (SQTS) was recently recognized as a familial clinical-electrocardiographic entity characterized by ion channel mutations, leading to sudden cardiac death, short refractoryExpand
Short QT Syndromes.
Today, the first choice therapy is implantable cardioverter-defibrillator implantation; however, pharmacologic treatment with hydroquinidine, which prolongs QT and reduces the inducibility of ventricular arrhythmias, may be proposed for children and probably for elderly asymptomatic patients. Expand
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Short QT syndrome.
Recent advances in understanding the idiopathic short QT syndrome are reviewed, discussing the basis of QT interval shortening, possible mechanisms for the associated arrhythmogenic risk in SQT1, current approaches to treatment of the SQTS (focusing on SQT 1) and avenues for future investigation. Expand


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