Identity of rearranged LINE/c-MYC junction sequences specific for the canine transmissible venereal tumor.

@article{Amariglio1991IdentityOR,
  title={Identity of rearranged LINE/c-MYC junction sequences specific for the canine transmissible venereal tumor.},
  author={E N Amariglio and Itzhak Hakim and Frida Brok-Simoni and Zehave Grossman and Nurit Katzir and Alon Harmelin and Bracha Ramot and Gideon Rechavi},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1991},
  volume={88 18},
  pages={8136-9}
}
The canine transmissible venereal tumor is a naturally occurring neoplastic disease that affects the external genitalia of both sexes and is transmitted during coitus. Cytogenetic and immunologic studies demonstrated that tumors from different parts of the world are very similar, suggesting that they are transferred from one animal to another by the transplantation of viable cells. We found that the c-MYC oncogene was rearranged in this tumor by the insertion of a transposable genetic element… CONTINUE READING

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