Identity of Leu-19 (CD56) leukocyte differentiation antigen and neural cell adhesion molecule

  title={Identity of Leu-19 (CD56) leukocyte differentiation antigen and neural cell adhesion molecule},
  author={Lewis L. Lanier and Roberto Testi and J M Bindl and Joseph H. Phillips},
  journal={The Journal of Experimental Medicine},
  pages={2233 - 2238}
Neural cell adhesion molecule (N-CAM) is a membrane glycoprotein expressed on neural and muscle tissues that is involved in homotypic adhesive interactions. We have demonstrated that N-CAM also is expressed on hematopoietic cells, and is recognized by the anti-Leu-19 mAb. Leu-19 is preferentially expressed on NK cells and T lymphocytes that mediate MHC-unrestricted cytotoxicity, but is also present on some myeloid leukemia cell lines. On NK cells, T cells, the KG1a.5 hematopoietic cell line… CONTINUE READING


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Neura l cell adhesion molecule

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