Identifying the stress transcriptome in the adrenal medulla following acute and repeated immobilization.

@article{Liu2008IdentifyingTS,
  title={Identifying the stress transcriptome in the adrenal medulla following acute and repeated immobilization.},
  author={Xiaoping Liu and Lidia I. Serova and Richard Kvetňansk{\'y} and Esther L. Sabban},
  journal={Annals of the New York Academy of Sciences},
  year={2008},
  volume={1148},
  pages={1-28}
}
Stress triggers changes in gene expression mediating important adaptive and maladaptive responses. The full repertoire of genes whose expression in the adrenal medulla is altered by stress has not been previously determined. In this study, gene profiling (RAE 230 2.0 Affymetrix) was applied to elucidate global changes in gene expression in adrenal medulla of rats exposed to 2-h immobilization (IMO) stress once or repeatedly for 6 consecutive days. The number of transcripts significantly (P < 0… CONTINUE READING

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