Identifying the role of Wilms tumor 1 associated protein in cancer prediction using integrative genomic analyses.

@article{Wu2016IdentifyingTR,
  title={Identifying the role of Wilms tumor 1 associated protein in cancer prediction using integrative genomic analyses.},
  author={Li-Sheng Wu and Jia-Yi Qian and Minghai Wang and Haiwei Yang},
  journal={Molecular medicine reports},
  year={2016},
  volume={14 3},
  pages={
          2823-31
        }
}
The Wilms tumor suppressor, WT1 was first identified due to its essential role in the normal development of the human genitourinary system. Wilms tumor 1 associated protein (WTAP) was subsequently revealed to interact with WT1 using yeast two-hybrid screening. The present study identified 44 complete WTAP genes in the genomes of vertebrates, including fish, amphibians, birds and mammals. The vertebrate WTAP proteins clustered into the primate, rodent and teleost lineages using phylogenetic tree… 

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