Identifying the important structural elements of brominated furanones for inhibiting biofilm formation by Escherichia coli.

Abstract

A collection of structurally closely related furanones was synthesized to identify the most important structural elements in brominated furanones for inhibiting the formation of bacterial biofilms. The results suggest that a conjugated exocyclic vinyl bromide on the furanone ring is the most important structural element for the non-toxic but inhibition… (More)
DOI: 10.1016/j.bmcl.2007.12.032

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@article{Han2008IdentifyingTI, title={Identifying the important structural elements of brominated furanones for inhibiting biofilm formation by Escherichia coli.}, author={Yongbin Han and Shuyu Hou and Karen A Simon and Dacheng Ren and Y Luk}, journal={Bioorganic & medicinal chemistry letters}, year={2008}, volume={18 3}, pages={1006-10} }