Identifying the Important HIV-1 Recombination Breakpoints

@article{Archer2008IdentifyingTI,
  title={Identifying the Important HIV-1 Recombination Breakpoints},
  author={John P. Archer and John W. Pinney and Jun Fan and Etienne Simon-Lori{\`e}re and Eric J. Arts and Matteo Negroni and David L. Robertson},
  journal={PLoS Computational Biology},
  year={2008},
  volume={4},
  pages={6900 - 6903}
}
Recombinant HIV-1 genomes contribute significantly to the diversity of variants within the HIV/AIDS pandemic. It is assumed that some of these mosaic genomes may have novel properties that have led to their prevalence, particularly in the case of the circulating recombinant forms (CRFs). In regions of the HIV-1 genome where recombination has a tendency to convey a selective advantage to the virus, we predict that the distribution of breakpoints--the identifiable boundaries that delimit the… CONTINUE READING
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