Identifying structural variation in haploid microbial genomes from short-read resequencing data using breseq

@inproceedings{Barrick2014IdentifyingSV,
  title={Identifying structural variation in haploid microbial genomes from short-read resequencing data using breseq},
  author={Jeffrey E Barrick and Geoffrey Colburn and Daniel E. Deatherage and Charles C. Traverse and Matthew D Strand and Jordan J Borges and David B. Knoester and Aaron Reba and Austin G. Meyer},
  booktitle={BMC Genomics},
  year={2014}
}
Mutations that alter chromosomal structure play critical roles in evolution and disease, including in the origin of new lifestyles and pathogenic traits in microbes. Large-scale rearrangements in genomes are often mediated by recombination events involving new or existing copies of mobile genetic elements, recently duplicated genes, or other repetitive sequences. Most current software programs for predicting structural variation from short-read DNA resequencing data are intended primarily for… CONTINUE READING
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