Identifying source proteins for MHC class I-presented peptides.

  title={Identifying source proteins for MHC class I-presented peptides.},
  author={Nathalie Vigneron and Wenbin Ma and Alexandre Michaux and Beno{\^i}t J Van den Eynde},
  journal={Methods in molecular biology},
Identification of antigenic peptides recognized by cytolytic T lymphocytes (CTL) is a prerequisite for the development of targeted cancer immunotherapy approaches. This chapter provides a global approach for the identification of peptides recognized by CTL. It implies the identification of the HLA molecule presenting the peptide as well as the design and screening of a cDNA library derived from the tumor cells. 
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