Identifying sexual differentiation genes that affect Drosophila life span

  title={Identifying sexual differentiation genes that affect Drosophila life span},
  author={Jie Shen and Daniel L. Ford and Gary N. Landis and J. E. Tower},
  booktitle={BMC geriatrics},
BACKGROUND Sexual differentiation often has significant effects on life span and aging phenotypes. For example, males and females of several species have different life spans, and genetic and environmental manipulations that affect life span often have different magnitude of effect in males versus females. Moreover, the presence of a differentiated germ-line has been shown to affect life span in several species, including Drosophila and C. elegans. METHODS Experiments were conducted to… CONTINUE READING

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Publications referenced by this paper.
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Understanding the Odd Science of Aging

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Highly Influenced

Drosophila germ-line modulation of insulin signaling and lifespan.

Proceedings of the National Academy of Sciences of the United States of America • 2008
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Endocrine regulation of aging and reproduction in Drosophila.

Molecular and cellular endocrinology • 2009
View 3 Excerpts

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