Identifying miRNAs, targets and functions

@inproceedings{Liu2014IdentifyingMT,
  title={Identifying miRNAs, targets and functions},
  author={Bing Liu and Jiuyong Li and Murray J. Cairns},
  booktitle={Briefings in Bioinformatics},
  year={2014}
}
microRNAs (miRNAs) are small endogenous non-coding RNAs that function as the universal specificity factors in post-transcriptional gene silencing. Discovering miRNAs, identifying their targets and further inferring miRNA functions have been a critical strategy for understanding normal biological processes of miRNAs and their roles in the development of disease. In this review, we focus on computational methods of inferring miRNA functions, including miRNA functional annotation and inferring… CONTINUE READING
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