Identifying meaningful intra-individual change standards for health-related quality of life measures.

@article{Wyrwich2000IdentifyingMI,
  title={Identifying meaningful intra-individual change standards for health-related quality of life measures.},
  author={Kathleen W. Wyrwich and Fredric D Wolinsky},
  journal={Journal of evaluation in clinical practice},
  year={2000},
  volume={6 1},
  pages={39-49}
}
Although numerous measures have been developed for the evaluation of health-related quality of life (HRQoL), strategies for identifying meaningful intra-individual change in these measures have not kept pace with instrument development. As a result, clinical trial researchers, quality assurance assessment teams and practising clinicians are without established standards to evaluate individual patient change in HRQoL measures as improved, stable or declined. This article reviews and critiques… CONTINUE READING
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