Identifying mRNA editing deaminase targets by RNA-Seq.

  title={Identifying mRNA editing deaminase targets by RNA-Seq.},
  author={Brad R. Rosenberg and Scott B. Dewell and F. Nina Papavasiliou},
  journal={Methods in molecular biology},
RNA editing deaminases act on a variety of targets in different organisms. A number of such enzymes have been shown to act on mRNA, with the resultant nucleotide changes modifying a transcript's information content. Though the deaminase activity of mRNA editing enzymes is readily demonstrated in vitro, identifying their physiological targets has proved challenging. Recent advances in ultra high-throughput sequencing technologies have allowed for whole transcriptome sequencing and expression… 
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Transposase mediated construction of RNA-seq libraries Material Supplemental
This paper is distributed exclusively by Cold Spring Harbor Laboratory Press for the first time and is distributed at a Creative Commons License (Attribution-NonCommercial 3.0 Unported License), as described.
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