Identifying drug-target proteins based on network features

@article{Zhu2009IdentifyingDP,
  title={Identifying drug-target proteins based on network features},
  author={Mingzhu Zhu and Lei Gao and Xia Li and Zhicheng Liu},
  journal={Science in China Series C: Life Sciences},
  year={2009},
  volume={52},
  pages={398-404}
}
Proteins rarely function in isolation inside and outside cells, but operate as part of a highly interconnected cellular network called the interaction network. Therefore, the analysis of the properties of drug-target proteins in the biological network is especially helpful for understanding the mechanism of drug action in terms of informatics. At present, no detailed characterization and description of the topological features of drug-target proteins have been available in the human protein… CONTINUE READING
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