Identifying differential expression in multiple SAGE libraries: an overdispersed log-linear model approach

@article{Lu2005IdentifyingDE,
  title={Identifying differential expression in multiple SAGE libraries: an overdispersed log-linear model approach},
  author={Jun Lu and John K. Tomfohr and Thomas B. Kepler},
  journal={BMC Bioinformatics},
  year={2005},
  volume={6},
  pages={165 - 165}
}
In testing for differential gene expression involving multiple serial analysis of gene expression (SAGE) libraries, it is critical to account for both between and within library variation. Several methods have been proposed, including the t test, t w test, and an overdispersed logistic regression approach. The merits of these tests, however, have not been fully evaluated. Questions still remain on whether further improvements can be made. In this article, we introduce an overdispersed log… CONTINUE READING
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