Identifying concerted evolution and gene conversion in mammalian gene pairs lasting over 100 million years

@article{Carson2009IdentifyingCE,
  title={Identifying concerted evolution and gene conversion in mammalian gene pairs lasting over 100 million years},
  author={Andrew R. Carson and Stephen W. Scherer},
  journal={BMC Evolutionary Biology},
  year={2009},
  volume={9},
  pages={156 - 156}
}
Concerted evolution occurs in multigene families and is characterized by stretches of homogeneity and higher sequence similarity between paralogues than between orthologues. Here we identify human gene pairs that have undergone concerted evolution, caused by ongoing gene conversion, since at least the human-mouse divergence. Our strategy involved the identification of duplicated genes with greater similarity within a species than between species. These genes were required to be present in… CONTINUE READING

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