Identifying and mapping cell-type-specific chromatin programming of gene expression.


A problem of substantial interest is to systematically map variation in chromatin structure to gene-expression regulation across conditions, environments, or differentiated cell types. We developed and applied a quantitative framework for determining the existence, strength, and type of relationship between high-resolution chromatin structure in terms of… (More)
DOI: 10.1073/pnas.1312523111

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