Identifying and Treating Opioid Side Effects: The Development of Methylnaltrexone
@article{Moss2019IdentifyingAT, title={Identifying and Treating Opioid Side Effects: The Development of Methylnaltrexone}, author={Jonathan Moss}, journal={Anesthesiology}, year={2019}, volume={130}, pages={142–148} }
Methylnaltrexone Reverses Chronic Opioid-induced Constipation: A Randomized, Controlled Trial. By Yuan CS, Foss JF, O’Connor M, Osinski J, Karrison T, Moss J, Roizen MF. JAMA 2000; 130:142–8. Reprinted with permission. Context: Constipation is the most common chronic adverse effect of opioid pain medications in patients who require long-term opioid administration, such as patients with advanced cancer, but conventional measures for ameliorating constipation often are insufficient. Objective: To…
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