Identifying Risk Factors for Severe Respiratory Syncytial Virus Among Infants Born After 33 Through 35 Completed Weeks of Gestation: Different Methodologies Yield Consistent Findings

@article{CarbonellEstrany2004IdentifyingRF,
  title={Identifying Risk Factors for Severe Respiratory Syncytial Virus Among Infants Born After 33 Through 35 Completed Weeks of Gestation: Different Methodologies Yield Consistent Findings},
  author={Xavier Carbonell‐Estrany and Josep Figueras-Aloy and Barbara J. Law},
  journal={The Pediatric Infectious Disease Journal},
  year={2004},
  volume={23},
  pages={S193-S201}
}
Background: Prematurity is a proven risk factor for severe respiratory syncytial virus (RSV) infection. Prematurity leads to an increased need for, and duration of, hospital admission, intensive care, mechanical ventilation and supplemental oxygen, as well as increased mortality. Methods: The Pediatric Investigators Collaborative Network on Infections in Canada (PICNIC) study was a prospective, multicenter, cohort study conducted in 16 regions across Canada during 2 successive RSV seasons… 

FLIP-2 Study: Risk Factors Linked to Respiratory Syncytial Virus Infection Requiring Hospitalization in Premature Infants Born in Spain at a Gestational Age of 32 to 35 Weeks

Logistic regression analysis demonstrated that the risk of RSV-related respiratory infection requiring hospital admission in preterm infants (32–35 WGA) was associated with the following factors: absolute chronologic age of ≤10 weeks at the onset ofRSV season, presence of school-age siblings or day care attendance and smoking during pregnancy.

Increased Risk for Respiratory Syncytial Virus-associated, Community-acquired Alveolar Pneumonia in Infants Born at 31–36 Weeks of Gestation

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The evolution of risk factors for respiratory syncytial virus-related hospitalisation in infants born at 32–35 weeks’ gestational age: time-based analysis using data from the FLIP-2 study

The risk of RSV hospitalisation appears to persist to at least 5–6 months old in 32–35 wGA infants, which has implications for the optimal management of disease prevention.

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Clinical relevance of prevention of respiratory syncytial virus lower respiratory tract infection in preterm infants born between 33 and 35 weeks gestational age

The causes and consequences of RSV LRTI in infants born 33–35 weeks GAA were determined via literature review, and the potential for using risk factors to identify high risk infants and optimise prophylaxis was looked at.

Respiratory syncytial virus risk factors in late preterm infants

  • M. LanariM. SilvestriG. Rossi
  • Medicine
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
  • 2009
On the basis of the finding that among nations the difference for severe RSV may exist in environmental and demographic risk factors, an ‘International’ tool has been developed based on the data from the Spanish FLIP study to predict the likelihood of RSV-hospitalization in newborns 33–35 WGA.

Respiratory Syncytial Virus-associated hospitalization in premature infants who did not receive palivizumab prophylaxis in Italy: a retrospective analysis from the Osservatorio Study

The hospitalized-to-not-hospitalized ratios and RSV+ frequency in the first 12 months of age in infants born prematurely confirm the vulnerability of these children for clinically important RSV infection, most notably in the <32 wGA category.

Development and Validation of a Risk Scoring Tool to Predict Respiratory Syncytial Virus Hospitalization in Premature Infants Born at 33 through 35 Completed Weeks of Gestation

TheRSV-RS accurately identified 33—35GA infants at increased risk for RSV-H in a Canadian cohort and external validation with Spanish case-control study data confirmed that the scoring tool is appropriate for the estimation of RSv-H risk.
...

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