Identifying Medication Targets for Psychostimulant Addiction: Unraveling the Dopamine D3 Receptor Hypothesis

@inproceedings{Keck2015IdentifyingMT,
  title={Identifying Medication Targets for Psychostimulant Addiction:
Unraveling the
Dopamine D3 Receptor Hypothesis},
  author={Thomas M Keck and William S. John and Paul W. Czoty and Michael A. Nader and Amy Hauck Newman},
  booktitle={Journal of medicinal chemistry},
  year={2015}
}
The dopamine D3 receptor (D3R) is a target for developing medications to treat substance use disorders. D3R-selective compounds with high affinity and varying efficacies have been discovered, providing critical research tools for cell-based studies that have been translated to in vivo models of drug abuse. D3R antagonists and partial agonists have shown… CONTINUE READING