Identifying Glioblastoma Gene Networks Based on Hypergeometric Test Analysis

@inproceedings{Stathias2014IdentifyingGG,
  title={Identifying Glioblastoma Gene Networks Based on Hypergeometric Test Analysis},
  author={Vasileios Stathias and Chiara Pastori and Tess Z. Griffin and Ricardo J. Komotar and Jennifer Clarke and Ming Zhang and Nagi George Ayad},
  booktitle={PloS one},
  year={2014}
}
Patient specific therapy is emerging as an important possibility for many cancer patients. However, to identify such therapies it is essential to determine the genomic and transcriptional alterations present in one tumor relative to control samples. This presents a challenge since use of a single sample precludes many standard statistical analysis techniques. We reasoned that one means of addressing this issue is by comparing transcriptional changes in one tumor with those observed in a large… CONTINUE READING