Identify biomarkers of neuropsychiatric systemic lupus erythematosus by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry combined with weak cation magnetic beads.

@article{Sun2011IdentifyBO,
  title={Identify biomarkers of neuropsychiatric systemic lupus erythematosus by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry combined with weak cation magnetic beads.},
  author={Ling Sun and Hua Chen and Chaojun Hu and Peng Wang and Yongzhe Li and Jing Xie and Fulin Tang and D. B. Margetson Ba and Xuan Zhang and Wei He},
  journal={The Journal of rheumatology},
  year={2011},
  volume={38 3},
  pages={
          454-61
        }
}
OBJECTIVE To identify proteomic biomarkers in cerebrospinal fluid (CSF) and develop a diagnostic proteomic model for neuropsychiatric systemic lupus erythematosus (NPSLE). METHODS CSF proteomic spectra were generated by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS) combined with weak cation exchange (WCX) magnetic beads. The spectra were taken from 27 patients with NPSLE before and after treatment, and 27 controls including 17 patients with… CONTINUE READING

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