Identifier sequences are transcribed specifically in brain

@article{Sutcliffe1984IdentifierSA,
  title={Identifier sequences are transcribed specifically in brain},
  author={J. Gregor Sutcliffe and Robert J. Milner and Joel M. Gottesfeld and Richard Allen Lerner},
  journal={Nature},
  year={1984},
  volume={308},
  pages={237-241}
}
Abstract‘Identifier’ or ID sequences are present in 62% of the RNA polymerase II and III transcripts made in vitro from brain nuclei but in fewer than 4% of the transcripts made from the nuclei of other tissues. An homologous 160-nucleotide cytoplasmic poly(A)+ RNA species, BC1, and a smaller species, BC2, are located in vivo exclusively in neural tissues. Cloned ID sequences are polymerase III templates in vitro. Our data suggest a model in which brain-specific polymerase III transcription of… CONTINUE READING
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