Identification of yeast Rho1p GTPase as a regulatory subunit of 1,3-beta-glucan synthase.

@article{Qadota1996IdentificationOY,
  title={Identification of yeast Rho1p GTPase as a regulatory subunit of 1,3-beta-glucan synthase.},
  author={Hiroshi Qadota and C P Python and Satoka Inoue and Mikio Arisawa and Yasuhiro Anraku and Y Zheng and Takuo Watanabe and David E. Levin and Yoshikazu Ohya},
  journal={Science},
  year={1996},
  volume={272 5259},
  pages={279-81}
}
1,3-beta-D-glucan synthase [also known as beta(1-->3) glucan synthase] is a multi-enzyme complex that catalyzes the synthesis of 1,3-beta-linked glucan, a major structural component of the yeast cell wall. Temperature-sensitive mutants in the essential Rho-type guanosine triphosphatase (GTPase), Rho1p, displayed thermolabile glucan synthase activity, which was restored by the addition of recombinant Rho1p. Glucan synthase from mutants expressing constitutively active Rho1p did not require… CONTINUE READING
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