Identification of yeast IQGAP (Iqg1p) as an anaphase-promoting-complex substrate and its role in actomyosin-ring-independent cytokinesis.

@article{Ko2007IdentificationOY,
  title={Identification of yeast IQGAP (Iqg1p) as an anaphase-promoting-complex substrate and its role in actomyosin-ring-independent cytokinesis.},
  author={Nolan Ko and Ryuichi Nishihama and Gregory H Tully and Denis Ostapenko and Mark J. Solomon and David O. Morgan and John R. Pringle},
  journal={Molecular biology of the cell},
  year={2007},
  volume={18 12},
  pages={
          5139-53
        }
}
In the yeast Saccharomyces cerevisiae, a ring of myosin II forms in a septin-dependent manner at the budding site in late G1. This ring remains at the bud neck until the onset of cytokinesis, when actin is recruited to it. The actomyosin ring then contracts, septum formation occurs concurrently, and cytokinesis is soon completed. Deletion of MYO1 (the only myosin II gene) is lethal on rich medium in the W303 strain background and causes slow-growth and delayed-cell-separation phenotypes in the… CONTINUE READING
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Global analysis of protein expression in yeast

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