Identification of virulence determinants of Mycobacterium avium that impact on the ability to resist host killing mechanisms

@inproceedings{Li2010IdentificationOV,
  title={Identification of virulence determinants of Mycobacterium avium that impact on the ability to resist host killing mechanisms},
  author={Yong-jun Li and Lia Danelishvili and Dirk Wagner and Mary Petrofsky and Luiz E. Bermudez},
  booktitle={Journal of medical microbiology},
  year={2010}
}
Mycobacterium avium is an opportunistic pathogen associated with pulmonary disease in non-AIDS patients and disseminated infection in patients with AIDS. The chief route of infection is by colonization and invasion of the mucosa of the gastrointestinal tract, but infection through the respiratory route also occurs. After crossing the mucosa, M. avium infects and replicates within tissue macrophages. To identify M. avium genes required for survival in vivo, a library of signature-tagged… CONTINUE READING

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