Identification of unique expression signatures and therapeutic targets in esophageal squamous cell carcinoma

@inproceedings{Yan2011IdentificationOU,
  title={Identification of unique expression signatures and therapeutic targets in esophageal squamous cell carcinoma},
  author={Wusheng Yan and Joanna H. Shih and Jaime Rodriguez-Canales and Michael A. Tangrea and Kris Ylaya and Jason D. Hipp and Audrey Player and Nan Hu and Alisa M Goldstein and Philip R. Taylor and Michael R. Emmert-Buck and Heidi S. Erickson},
  booktitle={BMC Research Notes},
  year={2011}
}
Esophageal squamous cell carcinoma (ESCC), the predominant histological subtype of esophageal cancer, is characterized by high mortality. Previous work identified important mRNA expression differences between normal and tumor cells; however, to date there are limited ex vivo studies examining expression changes occurring during normal esophageal squamous cell differentiation versus those associated with tumorigenesis. In this study, we used a unique tissue microdissection strategy and… CONTINUE READING

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