Identification of two teaghrelins in Shy-jih-chuen oolong tea.
@article{Li2019IdentificationOT, title={Identification of two teaghrelins in Shy-jih-chuen oolong tea.}, author={Yue-Chiun Li and Chieh-Ju Wu and Yi-Chiao Lin and Ruo-Hsuan Wu and Wen-Ying Chen and Ping-Chung Kuo and Jason T C Tzen}, journal={Journal of food biochemistry}, year={2019}, volume={43 4}, pages={ e12810 } }
Teaghrelins are unique acylated flavonoid tetraglycosides originally identified in Chin-shin oolong tea, and proposed to be potential oral analogs of ghrelin. Two acylated flavonoid tetraglycosides were isolated from Shy-jih-chuen oolong tea, and their chemical structures were determined to be quercetin and kaempferol 3-O-[α-L-arabinopyranosyl(1 → 3)][2"-O-(E)-p-coumaroyl] [β-D-glucopyranosyl(1 → 3)-α-L-rhamnopyranosyl(1 → 6)]-β-D-glucoside. These two compounds were extremely similar to the two…
5 Citations
Characterisation of teaghrelin-like principles from Assam tea cultivated in Thailand
- Chemistry, BiologyNatural product research
- 2020
Two new teaghrelin-like compounds were purified and characterised from Assam tea varieties collected in Thailand, and did not display notable anti-inflammatory activity in human neutrophils assay.
Characterization of teaghrelin-like compounds from tea cultivars
- ChemistryNatural product research
- 2019
Two new teaghrelin-like compounds were characterized from tea cultivars, and their chemical structures were established by the spectroscopic and spectrometric analysis, but due to the different location of rhamnose, these two teagh Relins may not show significant ghrelin receptor affinity.
Quercetin 3-O-malonylglucoside in the leaves of mulberry (Morus alba) is a functional analog of ghrelin.
- Medicine, ChemistryJournal of food biochemistry
- 2020
The relatively abundant compound, quercetin 3-O-malonylglucoside was subjected to a bioactivity assay, and the result confirmed that it was able to increase the growth hormone secretion of rat anterior pituitary cells and presumably a key ingredient for the anti-aging activity of mulberry leaves.
Anti-Inflammatory Principles from the Needles of Pinus taiwanensis Hayata and In Silico Studies of Their Potential Anti-Aging Effects
- BiologyAntioxidants
- 2021
Results suggest the flavonoids are responsible for the potential anti-aging effects of pine needle tea.
Teaghrelin Protects SH-SY5Y Cells against MPP+-Induced Neurotoxicity through Activation of AMPK/SIRT1/PGC-1α and ERK1/2 Pathways
- BiologyNutrients
- 2020
The neuroprotective potential of teaghrelin against PD was explored in a cell model in which human neuroblastoma SH-SY5Y cells were treated with the mitochondrial toxin 1-methyl-4-phenylpyridinium (MPP+).
References
SHOWING 1-10 OF 25 REFERENCES
Identification of biosynthetic intermediates of teaghrelins and teaghrelin-like compounds in oolong teas, and their molecular docking to the ghrelin receptor.
- Chemistry, BiologyJournal of food and drug analysis
- 2015
Teaghrelins, unique acylated flavonoid tetraglycosides in Chin-shin oolong tea, are putative oral agonists of the ghrelin receptor.
- Biology, ChemistryJournal of agricultural and food chemistry
- 2014
Two unique acylated flavonoid tetraglycosides previously identified in Chin-shin oolong tea were demonstrated to induce hunger of rats in a food intake assay and, thus, named teaghrelin-1 and teagh Relin-2, presumably, promising oral agonists of the ghrelin receptor.
Tea catechins and flavonoids from the leaves of Camellia sinensis inhibit yeast alcohol dehydrogenase.
- ChemistryBioorganic & medicinal chemistry
- 2012
Novel Acylated Flavonol Tetraglycoside with Inhibitory Effect on Lipid Accumulation in 3T3-L1 Cells from Lu'an GuaPian Tea and Quantification of Flavonoid Glycosides in Six Major Processing Types of Tea.
- Chemistry, MedicineJournal of agricultural and food chemistry
- 2017
Nine acylated FGs were found to inhibit the proliferation and differentiation of 3T3-L1 preadipocytes at concentrations of 25, 50, and 100 μM (P < 0.05) and a rapid UPLC method was established to quantify nine FGs in six major processing types of tea.
Ginkgoghrelins, unique acylated flavonoid diglycosides in Folium Ginkgo, stimulate growth hormone secretion via activation of the ghrelin receptor.
- Biology, ChemistryJournal of ethnopharmacology
- 2016
Massive accumulation of gallic acid and unique occurrence of myricetin, quercetin, and kaempferol in preparing old oolong tea.
- Chemistry, MedicineJournal of agricultural and food chemistry
- 2008
Analyzing infusions of three old and one newly prepared oolong teas showed that significant lower (-)-epigallocatechin gallate (EGCG) but higher gallic acid contents were detected in the old teas compared to the new one, suggesting the possibility of releasinggallic acid from EGCG in old tea preparation.
Relative content of gallic acid over 5-galloylquinic acid as an index for the baking intensity of oolong teas
- Medicine, ChemistryJournal of food and drug analysis
- 2018
Elucidation of physiological functions of tea catechins and their practical applications
- Medicine
- 2020
From 1996 onward, the defined tea catechin mixture, Polyphenon® E to the US National Cancer Institute for their chemoprevention clinical trials in over 20 instances, and in 2006, the US FDA approved the marketing of Polyphenons E ointment, Veregen®, as the first ”Botanical Drug” under FDA regulation.
Influence of gallic acid on α-amylase and α-glucosidase inhibitory properties of acarbose
- Medicine, ChemistryJournal of food and drug analysis
- 2016
Pancreatic lipase inhibition of strictinin isolated from Pu’er tea (Cammelia sinensis) and its anti-obesity effects in C57BL6 mice
- ChemistryJournal of Functional Foods
- 2018