Identification of two scyllo-inositol dehydrogenases in Bacillus subtilis.

@article{Morinaga2010IdentificationOT,
  title={Identification of two scyllo-inositol dehydrogenases in Bacillus subtilis.},
  author={Tetsuro Morinaga and Hitoshi Ashida and Ken-ichi Yoshida},
  journal={Microbiology},
  year={2010},
  volume={156 Pt 5},
  pages={1538-46}
}
scyllo-Inositol (SI) is a stereoisomer of inositol whose catabolism has not been characterized in bacteria. We found that Bacillus subtilis 168 was able to grow using SI as its sole carbon source and that this growth was dependent on a functional iol operon for catabolism of myo-inositol (MI; another inositol isomer, which is abundant in nature). Previous studies elucidated the MI catabolic pathway in B. subtilis as comprising multiple stepwise reactions catalysed by a series of Iol enzymes… CONTINUE READING

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