Identification of two proteins that interact with the Erp virulence factor from Mycobacterium tuberculosis by using the bacterial two-hybrid system

@article{Klepp2008IdentificationOT,
  title={Identification of two proteins that interact with the Erp virulence factor from Mycobacterium tuberculosis by using the bacterial two-hybrid system},
  author={Laura In{\'e}s Klepp and Marcelo Soria and Federico Carlos Blanco and Mar{\'i}a Ver{\'o}nica Bianco and Mar{\'i}a de la Paz Santangelo and Angel Cataldi and Fabiana Bigi},
  journal={BMC Molecular Biology},
  year={2008},
  volume={10},
  pages={3 - 3}
}
The exported repetitive protein (erp) gene encodes a secreted 36-kDa protein with a central domain containing several proline-glycine-leucine-threonine-serine (PGLTS) repeats. It has been demonstrated that erp is a virulence-associated factor since the disruption of this gene impairs the growth of Mycobacterium bovis and Mycobacterium tuberculosis in mice. In order to elucidate the function of Erp we searched for Erp-binding proteins from M. tuberculosis by using a bacterial two-hybrid system… CONTINUE READING

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References

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Showing 1-10 of 23 references

A bacterial two-hybrid system based on a reconstituted signal transduction pathway.

Proceedings of the National Academy of Sciences of the United States of America • 1998
View 4 Excerpts
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