Identification of tumorigenic retinal stem-like cells in human solid retinoblastomas

Abstract

Retinoblastoma (RB) is the most common malignant tumor of the retina in human children. Although it has been hypothesized for a long time that RB derives from multipotent retinal stem cells (RSCs) or retinoblasts, the direct evidence that the presence of tumorigenic RSCs in RB tumors is still lacking. Some studies indicate that malignant tumors contain… (More)
DOI: 10.1038/cr.2008.168

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